Jessa Crispin talks about Midwest fiction, and the lack of attention it gets. Part of it is that fiction has always been about going to places that weren't familair (Dorothy didn't go from Oz to Kansas) and I think that most people consider the Midwest boring, comfortable, and somewhere people want to leave. I know from living here all my life the Midwest is about as unfamiliar as you can get. The only difference between the eccentricities of the coasts and middle America is that in the former, the buildings are bigger.
I always write about Iowa (unless I'm writing about outer space, or that story in The Angler, where I flood nice, innocent Chicago). I'm writing a new story now that takes place in this fictional town I've made up. It just sort of happened. A lot of my short fiction (and the Angel Book) take place there. This new story gave me nothing but fits until the last couple days, when I happened upon the right approach (really experimental for me) and now it comes out in these great gushes. I'm trying to hold on for dear life when I'm writing it.